Pain：针灸可有效防治偏头痛复发和加重

记者从日前在京开会讨论的2011年医学亚太地区研讨会上告知，首都医科大学附属北京中医医院医学中心地带经流行病学证实，传统的中医医学疗法可有效性预防性全身性的病情恶化和很重。无关研究成果论文近日登载在亚太地区著名病理学期刊《呼吸困难》上，成为欧美大陆首篇登载于该杂志的流行病学论文。该文还被亚太地区知名病理学生物科学机构 Faculty of 1000 medicine（千名病理学家）附有。

据了解到，作为临床常见病之一，全身性发病率较低，且危害严重。现在，我国18岁~65岁人群的全身性死亡率较低达9.3%，且有逐年升较低渐进。医学治疗恶心在欧美已经有数千年的近现代。北京中医医院医学中心地带自2004年设立恶心专家门诊，开展了基于“绿叶王乐亭”、国医大师贺普仁等多位著名医学学家治痛经验的恶心研究成果。

据该中心地带主任王麟鹏引介，该项目采取单盲、双模拟、结果表明的形式，在国内5家医院的医学科共五招募140名无先兆全身性患者，随机分为两分组，则有治疗分组（医学加抗抑郁药）和对照分组（假针加氟桂利嗪）。两分组患者每周医学治疗3次，每晚口服药物。结果显示，4都将，治疗分组全身性的有效性缓解率为59%，对照分组为40%；治疗分组呼吸困难起算少于升高4.1天，对照分组少于升高1.9天。16都将，治疗分组有效性缓解率为56%，对照分组为37%；治疗分组呼吸困难起算少于升高 4.1天，对照分组少于升高2天。

研究成果人员据此确信，医学可以作为全身性的预防性病情恶化和很重的方法，其治果也优于此前国外的无关研究成果。由于其研究成果方法的独树一格和重要性，该论文还被亚太地区知名病理学生物科学机构“千名化学家”附有。（生物谷 Bioon.com）

doi:10.1016/j.pain.2011.04.006PMC:PMID:

Efficacy of acupuncture for migraine prophylaxis: A single-blinded, double-dummy, randomized controlled trial

Lin-Peng Wang,Xiao-Zhe Zhang,Jia Guo,Hui-Lin Liu,Yan Zhang,Cun-Zhi Liu,Jing-Hong Yi,Li-Ping Wang,Ji-Ping Zhao,Shan-Shan Li

Summary This multicenter, double-dummy trial suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks. Abstract Insufficient clinical trial data were ailable to prove the efficacy of acupuncture for migraine prophylaxis. A multicenter, double-dummy, single-blinded, randomized controlled clinical trial was conducted at the outpatient departments of acupuncture at 5 hospitals in China to evaluate the effectiveness of acupuncture. A total of 140 patients with migraine without aura were recruited and assigned randomly to 2 different groups: the acupuncture group treated with verum acupuncture plus placebo and the control group treated with sham acupuncture plus flunarizine. Treated by acupuncture 3 times per week and drugs every night, patients from both groups were evaluated at week 0 (baseline), week 4, and week 16. The primary outcome was measured by the proportion of responders (defined as the proportion of patients with a reduction of migraine days by at least 50%). The secondary outcome measures included the number of migraine days, visual ogue scale (VAS, 0 to 10cm) for pain, as well as the physical and mental component summary scores of the 36-item short-form health survey (SF-36). The patients in the acupuncture group had better responder rates and fewer migraine days compared with the control group (P.05). The results suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks, whereas no significantly differences were found between acupuncture and flunarizine in reduction of pain intensity and improvement of the quality of life.